The impact of iterative removal of low-information cluster-period cells from a stepped wedge design.

ABSTRACT:

Background

Standard stepped wedge trials, where clusters switch from the control to the intervention condition in a staggered manner, can be costly and burdensome. Recent work has shown that the amount of information contributed by each cluster in each period differs, with some cluster-periods contributing a relatively small amount of information. We investigate the patterns of the information content of cluster-period cells upon iterative removal of low-information cells, assuming a model for continuous outcomes with constant cluster-period size, categorical time period effects, and exchangeable and discrete-time decay intracluster correlation structures.

Methods

We sequentially remove pairs of "centrosymmetric" cluster-period cells from an initially complete stepped wedge

SUBMITTER: Rezaei-Darzi E 

PROVIDER: S-EPMC10324156 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature