Growth hormone treatment improves the development of follicles and oocytes in prepubertal lambs.

ABSTRACT:

Background

When prepubertal lambs are superovulated, the ovarian response to gonadotropin stimulation has great individual difference and the collected oocytes have lower developmental ability than that of adult ewes. Over the years, growth hormone (GH) has been used in assisted reproduction because it can improve the reproductive performance in humans and animals. However, the effect of GH on ovaries and oocytes of prepubertal lambs remains unclear.

Methods

Before and during follicle-stimulating hormone (FSH) superovulation of prepubertal lambs (4‒6-week-old), the lambs were treated with high (50 mg) or low dose (25 mg) of ovine GH in a long (5 days) or short (2 days) period. The recovered oocytes were used for in vitro maturation and fertilization, and several parameters o

SUBMITTER: Liu K 

PROVIDER: S-EPMC10324218 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature