Constructive on-DNA Thiol Aerial Oxidization for DNA-Encoded Library Synthesis.

ABSTRACT: A novel on-DNA oxidative disulfide formation method has been developed. Under ambient conditions, the methodology showcased wide applicability and swift implementation in routine DNA-encoded library synthesis to access pharmaceutically relevant motifs.

SUBMITTER: Xue L 

PROVIDER: S-EPMC10324384 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature