Exposure to soluble platinum salts in precious metal refinery workers over a 17-year period.

ABSTRACT:

Background

Occupational exposure to soluble chlorinated platinum (Pt) salts, commonly called chloroplatinates, is a known cause of Pt salt sensitisation (PSS) and occupational asthma. We aimed to model inhalable soluble Pt salts exposure levels based on measurements in precious metal refineries for use in a retrospective cohort study on PSS.

Methods

Five platinum refineries located in the United Kingdom (3 sites), United States, and South Africa provided time weighted average inhalable soluble Pt salts exposure data, measured in 2,982 personal air samples over a 17-year period (2000-2016). We used a Bayesian hierarchical model to estimate geometric mean (GM) exposure levels for each refinery and job title over time.

Results

The GM of measured exposure levels over all

SUBMITTER: Smit LAM 

PROVIDER: S-EPMC10324643 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature