Systemic cisplatin increases the number of patients showing positive off-frequency masking audiometry.

ABSTRACT:

Objective

The study aimed to evaluate the effect of systemic cisplatin administration on off-frequency masking audiometry.

Methods

Among 26 patients receiving systemic cisplatin, 48 ears were included in the analysis. All patients underwent pure-tone audiometry with ipsilateral narrow-band masking noise (off-frequency masking audiometry). In the off-frequency masking audiometry, 70 dBHL band-pass noise (center frequency 1000 Hz, 1/3 octave bandwidth) was administered to the tested ear. The acquired thresholds were compared to those of standard pure-tone audiometry, and threshold elevations greater than 10 dB were regarded as significant. The number of patients showing abnormal threshold elevation was compared between before and after the cisplatin administration.

Results<

SUBMITTER: Hiraumi H 

PROVIDER: S-EPMC10325046 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature