Multimodality OCT, IVUS and FFR evaluation of coronary intermediate grade lesions in women vs. men.

ABSTRACT:

Background

The pathophysiology of atherosclerotic plaque formation and its vulnerability seem to differ between genders due to contrasting risk profiles and sex hormones, however this process is still insufficiently understood. The aim of the study was to compare the differences between sexes regarding the optical coherence tomography (OCT), intravascular ultrasound (IVUS) and fractional flow reserve (FFR)-derived coronary plaque indices.

Methods

In this single-center multimodality imaging study patients with intermediate grade coronary stenoses identified in coronary angiogram (CAG) were evaluated using OCT, IVUS and FFR. Stenoses were considered significant when the FFR value was ≤0.8. Minimal lumen area (MLA), was analyzed by OCT in addition to plaque stratification into

SUBMITTER: Barus P 

PROVIDER: S-EPMC10325624 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature