Could axillary lymph node dissection be omitted in the mastectomy patient with tumor positive sentinel node?

ABSTRACT:

Background

Recent data from the ACOSOG Z0011 trial suggest that axillary lymph node dissection (ALND) may not be necessary for patients with positive sentinel lymph node biopsy (SLNB) receiving breast-conserving surgery (BCS) with irradiation. However, consensus statements and guidelines have recommended that patients undergoing mastectomy with tumor-positive sentinel node undergo completion ALND. In this study, we compared the locoregional recurrence rate of patients with tumor-positive sentinel nodes among three groups: mastectomy with SLNB, mastectomy with ALND and BCS with SLNB.

Method

We identified 6,163 women with invasive breast cancer who underwent surgical resection at our institution between January 2000 and December 2011. Clinicopathologic data obtained from the p

SUBMITTER: You JY 

PROVIDER: S-EPMC10325642 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature