Composition of subgingival microbiota associated with periodontitis and diagnosis of malignancy-a cross-sectional study.

ABSTRACT: Periodontitis is one of the world's most prevalent infectious conditions, affecting between 25 and 40% of the adult population. It is a consequence of the complex interactions between periodontal pathogens and their products, which trigger the host inflammatory response, chronic inflammation, and tissue destruction. Chronic systemic low-grade inflammation is involved in numerous diseases, and it is also known that long-lasting inflammation and chronic infections predispose one to cancer. Here, we characterized and compared the subgingival microbiota associated with periodontitis and diagnosis of malignancy in a longitudinal 10-year follow-up study. The study was conducted on 50 patients with periodontitis and 40 periodontally healthy individuals. The recorded clinical oral health parameter

SUBMITTER: Narayanan A 

PROVIDER: S-EPMC10325785 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature