Metabolic pathway prediction of core microbiome based on enterotype and orotype.

ABSTRACT:

Introduction

Identification of key microbiome components has been suggested to help address the maintenance of oral and intestinal health in humans. The core microbiome is similar in all individuals, whereas the diverse microbiome varies across individuals, based on their unique lifestyles and phenotypic and genotypic determinants. In this study, we aimed to predict the metabolism of core microorganisms in the gut and oral environment based on enterotyping and orotyping.

Materials and methods

Gut and oral samples were collected from 83 Korean women aged 50 years or older. The extracted DNA was subjected to next-generation sequencing analysis of 16S rRNA hypervariable regions V3-V4.

Results

Gut bacteria were clustered into three enterotypes, while oral bacteria were cl

SUBMITTER: Lee SH 

PROVIDER: S-EPMC10325833 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature