Phenotyping cardiogenic shock that showed different clinical outcomes and responses to vasopressor use: a latent profile analysis from MIMIC-IV database.

ABSTRACT:

Background

Cardiogenic shock (CS) is increasingly recognized as heterogeneous in its severity and response to therapies. This study aimed to identify CS phenotypes and their responses to the use of vasopressors.

Method

The current study included patients with CS complicating acute myocardial infarction (AMI) at the time of admission from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Laboratory and clinical variables were collected and used to conduct latent profile (LPA) analysis. Furthermore, we used a multivariable logistic regression (LR) model to explore the independent association between the use of vasopressors and endpoints.

Result

A total of 630 eligible patients with CS after AMI were enrolled in the study. The LPA identified three p

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10325854 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature