Prenatal lead exposure is negatively associated with the gut microbiome in childhood.

ABSTRACT:

Background

Metal exposures are associated with gut microbiome (GM) composition and function, and exposures early in development may be particularly important. Considering the role of the GM in association with many adverse health outcomes, understanding the relationship between prenatal metal exposures and the GM is critically important. However, there is sparse knowledge of the association between prenatal metal exposure and GM later in childhood.

Objectives

This analysis aims to identify associations between prenatal lead (Pb) exposure and GM composition and function in children 9-11 years old.

Methods

Data come from the Programming Research in Obesity, Growth, Environment and Social Stressors (PROGRESS) cohort based in Mexico City, Mexico. Prenatal metal concentrat

SUBMITTER: Eggers S 

PROVIDER: S-EPMC10325945 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature