Imaging findings for response evaluation of ductal carcinoma in situ in breast cancer patients treated with neoadjuvant systemic therapy: a systematic review and meta-analysis.

ABSTRACT:

Objectives

In approximately 45% of invasive breast cancer (IBC) patients treated with neoadjuvant systemic therapy (NST), ductal carcinoma in situ (DCIS) is present. Recent studies suggest response of DCIS to NST. The aim of this systematic review and meta-analysis was to summarise and examine the current literature on imaging findings for different imaging modalities evaluating DCIS response to NST. More specifically, imaging findings of DCIS pre- and post-NST, and the effect of different pathological complete response (pCR) definitions, will be evaluated on mammography, breast MRI, and contrast-enhanced mammography (CEM).

Methods

PubMed and Embase databases were searched for studies investigating NST response of IBC, including information on DCIS. Imaging findings and resp

SUBMITTER: Ploumen RAW 

PROVIDER: S-EPMC10326113 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature