Impact of non-regional lymph node metastases accurately revealed on ¹⁸F-PSMA-1007 PET/CT in the clinical management of metastatic hormone-sensitive prostate cancer.

ABSTRACT:

Background

Non-regional lymph node (NRLN) metastases has shown increasing importance in the prognosis evaluation and clinical management of primary metastatic hormone-sensitive prostate cancer (mHSPC). Hence, this study aimed to investigate the concordance rates between ¹⁸F-PSMA-1007 PET/CT and conventional imaging (CI) in revealing NRLN metastases, and explore the impact of NRLN metastases on the management of primary mHSPC.

Methods

The medical records of 224 patients with primary mHSPC were retrospectively reviewed, including 101 patients (45.1%) only received CI for TNM classification, 24 patients (10.7%) only received ¹⁸F-PSMA-1007 PET/CT, and 99 patients (44.2%) received both ¹⁸F-PSMA-1007 PET/CT and CI. Among patients who received

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC10326178 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature