Rhythmic oscillations in the midbrain dopaminergic nuclei in mice.

ABSTRACT:

Introduction

Dopamine release in the forebrain by midbrain ventral tegmental nucleus (VTA) and substantia nigra pars compacta (SNc) neurons is implicated in reward processing, goal-directed learning, and decision-making. Rhythmic oscillations of neural excitability underlie coordination of network processing, and have been reported in these dopaminergic nuclei at several frequency bands. This paper provides a comparative characterization of several frequencies of oscillations of local field potential and single unit activity, highlighting some behavioral correlates.

Methods

We recorded from optogenetically identified dopaminergic sites in four mice training in operant olfactory and visual discrimination tasks.

Results

Rayleigh and Pairwise Phase Consistency (PPC) anal

SUBMITTER: Oberto VJ 

PROVIDER: S-EPMC10326437 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature