Proton therapy for reducing heart and cardiac substructure doses in Indian breast cancer patients.

ABSTRACT:

Purpose

Indians have a higher incidence of cardiovascular diseases, often at a younger age, than other ethnic groups. This higher baseline risk requires consideration when assessing additional cardiac morbidity of breast cancer treatment. Superior cardiac sparing is a critical dosimetric advantage of proton therapy in breast cancer radiotherapy. We report here the heart and cardiac-substructure doses and early toxicities in breast cancer patients treated post-operatively with proton therapy in India's first proton therapy center.

Materials and methods

We treated twenty breast cancer patients with intensity-modulated proton therapy (IMPT) from October 2019 to September 2022, eleven after breast conservation, nine following mastectomy, and appropriate systemic therapy, when in

SUBMITTER: Nangia S 

PROVIDER: S-EPMC10326511 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature