Peripheral Artery Disease and Subsequent Risk of Infectious Disease in Older Individuals: The ARIC Study.

ABSTRACT:

Objective

To quantify the association of peripheral artery disease (PAD) with infection risk because PAD has been understudied despite recognition of atherosclerotic cardiovascular disease as a risk factor for infection.

Methods

Among 5082 participants of the Atherosclerosis Risk in Communities study (aged 71 to 90 years during 2011-2013), we assessed the association of PAD status, based on clinical history and ankle-brachial index (ABI), with infection-related hospitalization (through December 2019) using multivariable Cox regression. We also cross-classified participants by PAD and coronary heart disease (CHD)/stroke status at baseline, with implications for polyvascular disease.

Results

During the median follow-up of 6.5 years, there were 1677 infection-related hos

SUBMITTER: Mok Y 

PROVIDER: S-EPMC10326620 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature