Urine metabolites and viral pneumonia among children: a case-control study in China.

ABSTRACT:

Background

Viral pneumonia in children is common and has grave consequences. The study aims to better understand the pathophysiological processes involved in the onset and progression of viral pneumonia and identify common effects or biomarkers across different viruses.

Methods

This study collected urine samples from 96 patients with viral pneumonia including respiratory syncytial virus (RSV) (n=30), influenza virus (IV) (n=23), parainfluenza virus (PIV) (n=24), and adenovirus (ADV) (n=19), and 31 age- and sex-matched normal control (NC) subjects. The samples were analyzed using liquid chromatography coupled with mass spectrometry (LC-MS) to identify endogenous substances. The XCMS Online platform was utilized for data processing and analysis , including feature detection, r

SUBMITTER: Liu C 

PROVIDER: S-EPMC10326753 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature