K-means cluster analysis of characteristic patterns of allergen in different ages: Real life study.

ABSTRACT:

Background

Atopy varies in people of different ages owing to different physical conditions and exposure to allergens. We aimed to cluster ages based on atopic severity using K-means cluster analysis and identify atopic incidence, severity, as well as the association among peripheral eosinophils, IgE and sensitisation.

Methods

Consecutive patients (n = 7654) with allergic symptoms and undergoing allergen-specific IgE tests were included from 2013 to 2017. Age, sex, specific-IgE, peripheral eosinophil counts and total-IgE were collected.

Results

Five age categories were identified: 1-17, 18-36, 37-52, 53-69 and 70-100 years. The incidences of atopy and poly-sensitisation decreased with increasing age. Similar trend was observed for aeroallergens, egg and milk but not fo

SUBMITTER: Zhao L 

PROVIDER: S-EPMC10326892 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature