A Systematic Review of Clinical Trials in Uveitis: Lessons Learned.

ABSTRACT:

Purpose

Clinical trials in uveitis have led to the expansion of therapeutic options for the management of non-infectious uveitis. The purpose of this systematic review is to investigate why some clinical trials have yielded successful results and regulatory approval of new therapies, and some have not.

Methods

A systematic literature search of the Pubmed/MEDLINE database and clinicaltrials.gov was performed from 2006 to 2021, according to the PRISMA guidelines. Phase III clinical trials of systemic and local therapies in adults with non-infectious intermediate, posterior, and panuveitis were included.

Results

A total of 79 clinical trials were collected from ClinicalTrials.gov and PubMed/MEDLINE database search. Based on the inclusion and exclusion criteria, 14 clinic

SUBMITTER: Lobo-Chan AM 

PROVIDER: S-EPMC10326894 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature