S100A family is a group of immune markers associated with poor prognosis and immune cell infiltration in hepatocellular carcinoma.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) is one of the most common human cancers with poor prognosis in the world. HCC has become the second leading cause of cancer-related death in China. It is urgent to identify novel biomarker and valid target to effectively diagnose, treat or predict the prognosis of HCC. It has been reported that S100A family is closely related to cell proliferation and migration of different cancers. However, the values of S100As in HCC remain to be further analyzed.

Methods

We investigated the transcriptional and translational expression of S100As, as well as the value of this family in HCC patients from the various databases.

Results

S100A10 was most relevant to HCC.

Conclusions

The results from HCC patients' tissues and different cell

SUBMITTER: Qi Y 

PROVIDER: S-EPMC10327351 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature