Machine learning for predicting the risk stratification of 1-5 cm gastric gastrointestinal stromal tumors based on CT.

ABSTRACT:

Backgroud

To predict the malignancy of 1-5 cm gastric gastrointestinal stromal tumors (GISTs) by machine learning (ML) on CT images using three models - Logistic Regression (LR), Decision Tree (DT) and Gradient Boosting Decision Tree (GBDT).

Methods

231 patients from Center 1 were randomly assigned into the training cohort (n = 161) and the internal validation cohort (n = 70) in a 7:3 ratio. The other 78 patients from Center 2 served as the external test cohort. Scikit-learn software was used to build three classifiers. The performance of the three models were evaluated by sensitivity, specificity, accuracy, positive predictive value (PPV), negative predictive value (NPV) and area under the curve (AUC). Diagnostic differences between ML models and radiologists were compared

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10327391 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature