Validation of the children international IgA nephropathy prediction tool based on data in Southwest China.

ABSTRACT:

Background

Immunoglobulin A nephropathy (IgAN) is one of the most common kidney diseases leading to renal injury. Of pediatric cases, 25%-30% progress into end-stage kidney disease (ESKD) in 20-25 years. Therefore, predicting and intervening in IgAN at an early stage is crucial. The purpose of this study was to validate the availability of an international predictive tool for childhood IgAN in a cohort of children with IgAN treated at a regional medical centre.

Methods

An external validation cohort of children with IgAN from medical centers in Southwest China was formed to validate the predictive performance of the two full models with and without race differences by comparing four measures: area under the curve (AUC), the regression coefficient of linear prediction (PI), su

SUBMITTER: Yu X 

PROVIDER: S-EPMC10327563 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature