Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations.

ABSTRACT: Simulation is a key tool in population genetics for both methods development and empirical research, but producing simulations that recapitulate the main features of genomic datasets remains a major obstacle. Today, more realistic simulations are possible thanks to large increases in the quantity and quality of available genetic data, and the sophistication of inference and simulation software. However, implementing these simulations still requires substantial time and specialized knowledge. These challenges are especially pronounced for simulating genomes for species that are not well-studied, since it is not always clear what information is required to produce simulations with a level of realism sufficient to confidently answer a given question. The community-developed framework stdpopsi

SUBMITTER: Lauterbur ME 

PROVIDER: S-EPMC10328510 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature