Child Aflatoxin Exposure is Associated with Poor Child Growth Outcomes: A Prospective Cohort Study in Rural Malawi.

ABSTRACT:

Background

Aflatoxin (AF) exposure is associated with child growth faltering in cross-sectional studies, with limited findings from longitudinal studies.

Objectives

To evaluate the relationship between maternal AF B₁-lysine adduct concentration, child AF B₁-lysine adduct concentration, and child growth in the first 30 mo of life.

Methods

AF B₁-lysine adduct was measured in mother-child dyad plasma samples using isotope dilution mass spectrometry. Using linear regression, we assessed the relationship between AF B₁-lysine adduct concentration and child weight, height, and head and mid-upper arm circumferences at 1 wk, 6, 12, 18, 24, and 30 mo of age.

Results

In adjusted models, maternal prenatal AF B₁-lysine

SUBMITTER: Matchado A 

PROVIDER: S-EPMC10328803 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature