Early functional connectivity alterations in contralesional motor networks influence outcome after severe stroke: a preliminary analysis.

ABSTRACT: Connectivity studies have significantly extended the knowledge on motor network alterations after stroke. Compared to interhemispheric or ipsilesional networks, changes in the contralesional hemisphere are poorly understood. Data obtained in the acute stage after stroke and in severely impaired patients are remarkably limited. This exploratory, preliminary study aimed to investigate early functional connectivity changes of the contralesional parieto-frontal motor network and their relevance for the functional outcome after severe motor stroke. Resting-state functional imaging data were acquired in 19 patients within the first 2 weeks after severe stroke. Nineteen healthy participants served as a control group. Functional connectivity was calculated from five key motor areas of the parieto-

SUBMITTER: Braaß H 

PROVIDER: S-EPMC10328915 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature