Diabetic retinopathy is a predictor of chronic respiratory failure: A nationwide register-based cohort study.

ABSTRACT:

Purpose

Diabetic retinopathy (DR) is a hypoxic retinal disease, but so far, the association with systemic hypoxia is poorly understood. Hence, the aim of this study was to evaluate cross-sectional and longitudinal associations between DR and chronic respiratory failure (CRF) in a national cohort.

Design

Cross-sectional and 5-year longitudinal register-based cohort study.

Methods

Between 2013 and 2018, we included patients with diabetes from the Danish Registry of Diabetic Retinopathy, who were each age and sex matched with five controls without diabetes. At index date, the prevalence of CRF was compared between cases and controls, and the longitudinal relationship between DR and CRF was assessed in a five-year follow-up.

Results

At baseline, we identified 1,980

SUBMITTER: Thinggaard BS 

PROVIDER: S-EPMC10329134 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature