Comparison of phenprocoumon with direct oral anticoagulants in catheter ablation of atrial fibrillation.

ABSTRACT:

Aims

In patients undergoing catheter ablation for atrial fibrillation (AF), direct oral anticoagulants (DOACs) are as effective and safe as the vitamin K antagonist (VKA) warfarin. Phenprocoumon has a different pharmacokinetic profile compared with warfarin and is the most used VKA in Germany. The aim of the study was to compare DOAC with phenprocoumon.

Methods and results

In this retrospective single-centre cohort study, 1735 patients who underwent 2219 consecutive catheter ablations for AF between January 2011 and May 2017 were included. All patients were in-hospital for at least 48 h after catheter ablation. The primary outcome was defined as peri-procedural thrombo-embolic events. The secondary outcome was any bleeding according to the International Society on Thrombosis

SUBMITTER: Gjermeni D 

PROVIDER: S-EPMC10329261 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature