Oral colonization by gram-negative bacilli in patients with hematologic malignancies and solid tumors compared with healthy controls.

ABSTRACT:

Background

Colonization of the oropharynx with gram-negative bacilli (GNB) is considered a negative prognostic factor in immunocompromised individuals. Hemato-oncologic patients represent a high-risk group due to their immunodeficiencies and associated treatments. This study aimed to determine the rates of oral colonization by GNB, associated factors, and clinical outcomes in patients with hematologic malignancies and solid tumors compared with healthy subjects.

Methods

We conducted a comparative study of hemato-oncologic patients and healthy subjects from August to October 2022. Swabs were taken from the oral cavity; specimens with GNB were identified and tested for antimicrobial susceptibility.

Results

We included 206 participants (103 hemato-oncologic patients and

SUBMITTER: Santibanez-Bedolla KE 

PROVIDER: S-EPMC10329337 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature