A novel method for assessment of airway opening pressure without the need for low-flow insufflation.

ABSTRACT:

Background

Airway opening pressure (AOP) detection and measurement are essential for assessing respiratory mechanics and adapting ventilation. We propose a novel approach for AOP assessment during volume assist control ventilation at a usual constant-flow rate of 60 L/min.

Objectives

To validate the conductive pressure (P_cond) method, which compare the P_cond-defined on the airway pressure waveform as the difference between the airway pressure level at which an abrupt change in slope occurs at the beginning of insufflation and PEEP-to resistive pressure for AOP detection and measurement, and to compare its respiratory and hemodynamic tolerance to the standard low-flow insufflation method.

Methods

The proof-of-concept of the P_cond method

SUBMITTER: Haudebourg AF 

PROVIDER: S-EPMC10329375 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature