Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep.

ABSTRACT:

Background

Wool fibers are valuable materials for textile industry. Typical wool fibers are divided into medullated and non-medullated types, with the former generated from primary wool follicles and the latter by either primary or secondary wool follicles. The medullated wool is a common wool type in the ancestors of fine wool sheep before breeding. The fine wool sheep have a non-medullated coat. However, the critical period determining the type of wool follicles is the embryonic stage, which limits the phenotypic observation and variant contrast, making both selection and studies of wool type variation fairly difficult.

Results

During the breeding of a modern fine (MF) wool sheep population with multiple-ovulation and embryo transfer technique, we serendipitously discovere

SUBMITTER: Wang J 

PROVIDER: S-EPMC10329393 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature