Does childhood maltreatment or current stress contribute to increased risk for major depression during the menopause transition?

ABSTRACT:

Background

The menopausal transition (MT) poses an increased risk for major depression (MD), but not for all women. Current and past stress are toxic risk factors for depression throughout life. The MT may be a time of increased sensitivity to stress, especially among women with a lifetime history of major depressive disorder (MDD). We evaluated whether women who experienced childhood maltreatment (CM) or current stressful events or ongoing problems were at increased risk for MD during the MT.

Methods

At the Pittsburgh site of the Study of Women's Health Across the Nation, 333 midlife women were interviewed approximately annually over 15 years with the Structured Clinical Interview for the Diagnosis of DSM-IV Axis I Disorders and provided health and psychosocial data includi

SUBMITTER: Bromberger JT 

PROVIDER: S-EPMC10329560 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature