Multimorbidity prevalence and patterns in chronic kidney disease: findings from an observational multicentre UK cohort study.

ABSTRACT:

Purpose

Multimorbidity [defined as two or more long-term conditions (LTCs)] contributes to increased treatment and medication burden, poor health-related quality of life, and worse outcomes. Management strategies need to be patient centred and tailored depending on existing comorbidities; however, little is known about the prevalence and patterns of comorbidities in people with chronic kidney disease (CKD). We investigated the prevalence of multimorbidity and comorbidity patterns across all CKD stages.

Methods

Multimorbidity was assessed, using a composite of self-report and clinical data, across four CKD groups stratified by eGFR [stage 1-2, stage 3a&b, stage 4-5, and kidney transplant (KTx)]. Principal component analysis using varimax rotation was used to identify comorbid

SUBMITTER: Hawthorne G 

PROVIDER: S-EPMC10329585 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature