Effects of Nystatin oral rinse on oral Candida species and Streptococcus mutans among healthy adults.

ABSTRACT:

Objectives

To examine the effect of Nystatin oral rinse on oral Candida species and Streptococcus mutans carriage.

Materials and methods

Twenty healthy adults with oral candidiasis participated in the single-arm clinical trial and received Nystatin oral rinse for 7 days, 4 applications/day, and 600,000 International Units/application. Demographic-socioeconomic-oral-medical conditions were obtained. Salivary and plaque Candida species and Streptococcus mutans were assessed at baseline and 1-week and 3-month follow-ups. Twenty-four salivary cytokines were assessed. Candida albicans isolates underwent Nystatin susceptibility test.

Results

Half of participants (10/20) were free of salivary C. albicans after using Nystatin rinse. Salivary S. mutans was significantly reduce

SUBMITTER: Aljaffary M 

PROVIDER: S-EPMC10329597 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature