Predictability performance of urinary C-C motif chemokine ligand 14 and renal resistive index for persistent sepsis-associated acute kidney injury in ICU patients.

ABSTRACT:

Objectives

The performance of renal resistance index (RRI) in predicting persistent sepsis-associated acute kidney injury (S-AKI) remains debatable, and the value of urinary C-C motif chemokine ligand 14 (CCL14) in predicting persistent S-AKI has not been validated yet. Therefore, we aimed to determine the applicability of a urinary biomarker CCL14 for the early detection of persistent S-AKI. Furthermore, the use of RRI obtained from renal Doppler ultrasonography was applied to differentiate transient from persistent S-AKI. Finally, we aimed to evaluate the use of these techniques in predicting different subtypes of S-AKI.

Methods

This prospective observational study was conducted at the internal medicine intensive care unit (ICU) of a university hospital. The RRI was determ

SUBMITTER: Jiang W 

PROVIDER: S-EPMC10329624 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature