Global within-species phylogenetics of sewage microbes suggest that local adaptation shapes geographical bacterial clustering.

ABSTRACT: Most investigations of geographical within-species differences are limited to focusing on a single species. Here, we investigate global differences for multiple bacterial species using a dataset of 757 metagenomics sewage samples from 101 countries worldwide. The within-species variations were determined by performing genome reconstructions, and the analyses were expanded by gene focused approaches. Applying these methods, we recovered 3353 near complete (NC) metagenome assembled genomes (MAGs) encompassing 1439 different MAG species and found that within-species genomic variation was in 36% of the investigated species (12/33) coherent with regional separation. Additionally, we found that variation of organelle genes correlated less with geography compared to metabolic and membrane genes,

SUBMITTER: Jespersen ML 

PROVIDER: S-EPMC10329687 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature