Targeted metabolomic profiling as a tool for diagnostics of patients with non-small-cell lung cancer.

ABSTRACT: Lung cancer is referred to as the second most common cancer worldwide and is mainly associated with complex diagnostics and the absence of personalized therapy. Metabolomics may provide significant insights into the improvement of lung cancer diagnostics through identification of the specific biomarkers or biomarker panels that characterize the pathological state of the patient. We performed targeted metabolomic profiling of plasma samples from individuals with non-small cell lung cancer (NSLC, n = 100) and individuals without any cancer or chronic pathologies (n = 100) to identify the relationship between plasma endogenous metabolites and NSLC by means of modern comprehensive bioinformatics tools, including univariate analysis, multivariate analysis, partial correlation network analysis a

SUBMITTER: Shestakova KM 

PROVIDER: S-EPMC10329697 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature