Salivary Cortisol Dynamics After Mild Traumatic Brain Injury.

ABSTRACT:

Objective

To assess mild traumatic brain injury (mTBI)-related alterations in baseline (resting) salivary cortisol and cortisol reactivity to cognitive and exercise stressors, which are frequently encountered during mTBI rehabilitation and recovery.

Setting

Persons with mTBI were recruited from a level 1 trauma center emergency department. Uninjured controls (UCs) were recruited from the community.

Participants

Participants were 37 individuals with mTBI and 24 UCs. All patients with mTBI were enrolled at 7 ± 3 days post-injury, met the American Congress of Rehabilitation Medicine definition of mTBI, and had no acute intracranial findings on clinical neuroimaging (if performed).

Design

A prospective cohort study design was used. All participants provided saliva

SUBMITTER: Musacchio S 

PROVIDER: S-EPMC10329977 | biostudies-literature | 2023 Jul-Aug 01

REPOSITORIES: biostudies-literature