Performance of a modified fracture risk assessment tool for fragility fracture prediction among older veterans living with HIV.

ABSTRACT:

Objective

Fragility fractures (fractures) are a critical outcome for persons aging with HIV (PAH). Research suggests that the fracture risk assessment tool (FRAX) only modestly estimates fracture risk among PAH. We provide an updated evaluation of how well a 'modified FRAX' identifies PAH at risk for fractures in a contemporary HIV cohort.

Design

Cohort study.

Methods

We used data from the Veterans Aging Cohort Study to evaluate veterans living with HIV, aged 50+ years, for the occurrence of fractures from 1 January 2010 through 31 December 2019. Data from 2009 were used to evaluate the eight FRAX predictors available to us: age, sex, BMI, history of previous fracture, glucocorticoid use, rheumatoid arthritis, alcohol use, and smoking status. These predictor values we

SUBMITTER: Womack JA 

PROVIDER: S-EPMC10329997 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature