Comparative genomics of the Liberibacter genus reveals widespread diversity in genomic content and positive selection history.

ABSTRACT: 'Candidatus Liberibacter' is a group of bacterial species that are obligate intracellular plant pathogens and cause Huanglongbing disease of citrus trees and Zebra Chip in potatoes. Here, we examined the extent of intra- and interspecific genetic diversity across the genus using comparative genomics. Our approach examined a wide set of Liberibacter genome sequences including five pathogenic species and one species not known to cause disease. By performing comparative genomics analyses, we sought to understand the evolutionary history of this genus and to identify genes or genome regions that may affect pathogenicity. With a set of 52 genomes, we performed comparative genomics, measured genome rearrangement, and completed statistical tests of positive selection. We explored ma

SUBMITTER: Batarseh TN 

PROVIDER: S-EPMC10330825 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature