Genetic diversity and selection of Tibetan sheep breeds revealed by whole-genome resequencing.

ABSTRACT:

Objective

This study aimed to elucidate the underlying gene regions responsible for productive, phenotypic or adaptive traits in different ecological types of Tibetan sheep and the discovery of important genes encoding valuable traits.

Methods

We used whole-genome resequencing to explore the genetic relationships, phylogenetic tree, and population genetic structure analysis. In addition, we identified 28 representative Tibetan sheep single-nucleotide polymorphisms (SNPs) and genomic selective sweep regions with different traits in Tibetan sheep by fixation index (Fst) and the nucleotide diversity (θπ) ratio.

Results

The genetic relationships analysis showed that each breed partitioned into its own clades and had close genetic relationships. We also identified many pot

SUBMITTER: Tian D 

PROVIDER: S-EPMC10330983 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature