Ontology highlight
ABSTRACT:
SUBMITTER: Drabczyk AK
PROVIDER: S-EPMC10331126 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Drabczyk Anna K AK Kułaga Damian D Zaręba Przemysław P Tylińska Wiktoria W Bachowski Wojciech W Archała Aneta A Wnorowski Artur A Tzani Andromachi A Detsi Anastasia A Jaśkowska Jolanta J
RSC advances 20230710 30
New derivatives of the known antipsychotic drug olanzapine have been obtained as potential compounds with anticancer activity in two metabolically different breast cancer cell lines: MCF-7 and triple negative MDA-MB-231. The compounds were obtained under phase transfer catalysis (PTC) in the presence of microwave irradiation (MW) or ultrasound (")))"), evaluating the effect of solvents such as dimethylformamide, water, or choline chloride/urea (natural deep eutectic solvent, NaDES). In the best ...[more]