Can we forecast poor outcome in herpes simplex and varicella zoster encephalitis? A narrative review.

ABSTRACT: Herpes simplex virus (HSV) and varicella zoster virus (VZV) are among the most commonly diagnosed infectious causes of sporadic encephalitis worldwide. Despite treatment, mortality and morbidity rates remain high, especially for HSV encephalitis. This review is intended to provide an overview of the existing scientific literature on this topic from the perspective of a clinician who is confronted with serious decisions about continuation or withdrawal of therapeutic interventions. We performed a literature review searching two databases and included 55 studies in the review. These studies documented or investigated specifically outcome and predictive parameters of outcome of HSV and/or VZV encephalitis. Two reviewers independently screened and reviewed full-text articles meeting the inclus

SUBMITTER: Abbuehl LS 

PROVIDER: S-EPMC10331601 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature