Long-term outcome analysis of Y90 radioembolization in hepatocellular carcinoma.

ABSTRACT:

Background

Yttrium-90 (Y90) radioembolization is a catheter-based therapy for hepatocellular carcinoma (HCC). Multiple trials have evaluated the efficacy of Y90 in HCC; however, few have assessed long-term hepatic function. This study aimed to evaluate a clinical real-world experience of Y90 effectiveness and long-term impact on hepatic function.

Methods

A single-center retrospective chart review was performed for patients with Child-Pugh (CP) class A or B who received Y90 for primary HCC between 2008 and 2016. Model for end-stage liver disease (MELD) and CP scores were calculated on the day of treatment and 1, 3, 6, 12, and 24 months post-procedure.

Results

Of the 134 patients included, the mean age was 60 years old and median overall survival (OS) from date of diagn

SUBMITTER: Lee HM 

PROVIDER: S-EPMC10331743 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature