Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane.

ABSTRACT: A general microwave synthesis of 4-oxo-3,4-dihydroquinazolin-2-yl propanoic acids and their diamide precursors from the corresponding substituted benzamide and succinic anhydride is described, using pinane as a sustainable solvent that favors the cyclization step. The conditions are some of the most simple and cost effective reported.

SUBMITTER: Richieu A 

PROVIDER: S-EPMC10331922 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature