Associations between an obesity-related dietary pattern and incidence of overall and site-specific cancers: a prospective cohort study.

ABSTRACT:

Background

A dietary pattern (DP) may impact on cancer incidence more strongly than individual foods, but this association remains uncertain. Here, we aimed to broadly explore the associations of an obesity-related DP with overall and 19 site-specific cancers.

Methods

This study included 114,289 cancer-free participants with at least two dietary assessments. A total of 210 food items were classified into 47 food groups, and the mean amount of each food group was used in reduced-rank regression to derive the obesity-related DP. Cox regressions were conducted to explore the associations of the obesity-related DP with overall and 19 site-specific cancers. The parallel mediation model was constructed to quantify the mediating roles of potential mediators.

Results

During a

SUBMITTER: Maimaitiyiming M 

PROVIDER: S-EPMC10332028 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature