Microbiota and mycobiota in bronchoalveolar lavage fluid of silicosis patients.

ABSTRACT:

Background

The contribution of bronchoalveolar lavage fluid (BALF) microbiota and mycobiota to silicosis has recently been noticed. However, many confounding factors can influence the accuracy of BALF microbiota and mycobiota studies, resulting in inconsistencies in the published results. In this cross-sectional study, we systematically investigated the effects of "sampling in different rounds of BALF" on its microbiota and mycobiota. We further explored the relationship between silicosis fatigue and the microbiota and mycobiota.

Methods

After obtaining approval from the ethics board, we collected 100 BALF samples from 10 patients with silicosis. Demographic data, clinical information, and blood test results were also collected from each patient. The characteristics of the m

SUBMITTER: Xie L 

PROVIDER: S-EPMC10332100 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature