Trends in overdose deaths involving gabapentinoids and Z-drugs in the United States.

ABSTRACT:

Introduction

As policies have been implemented to limit access to prescription opioids, other drugs have been prescribed off-label, sometimes concurrently with opioids, to manage pain. There are concerns about the use of gabapentinoids and "Z-drugs" with opioids. As the opioid crisis transitions to illicit opioids and polysubstance use, little work quantifies the concurrent involvement of non-opioid prescription drugs and illicit opioids in overdose deaths.

Methods

Data from the census of deaths in the United States for 1999-2020 were used to understand trends in deaths involving gabapentinoids/Z-drugs and opioid co-involvement. These trends were studied overall and by sex, race, age, and education.

Results

Per capita overdose deaths involving gabapentinoids/Z-drugs i

SUBMITTER: Powell D 

PROVIDER: S-EPMC10332434 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature