Mild antecedent COVID-19 associated with symptom-specific post-acute sequelae.

ABSTRACT:

Background

The impact of COVID-19 severity on development of long-term sequelae remains unclear, and symptom courses are not well defined.

Methods

This ambidirectional cohort study recruited adults with new or worsening symptoms lasting ≥3 weeks from confirmed SARS-CoV-2 infection between August 2020-December 2021. COVID-19 severity was defined as severe for those requiring hospitalization and mild for those not. Symptoms were collected using standardized questionnaires. Multivariable logistical regression estimated odds ratios (OR) and 95% confidence intervals (CI) for associations between clinical variables and symptoms.

Results

Of 332 participants enrolled, median age was 52 years (IQR 42-62), 233 (70%) were female, and 172 (52%) were African American. Antecedent C

SUBMITTER: Walker TA 

PROVIDER: S-EPMC10332615 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature