Botulism due to Injection Drug Use.

ABSTRACT:

Audience

This scenario was developed to educate emergency medicine residents on the diagnosis and management of wound botulism secondary to injection drug use.

Introduction

Botulism is a relatively rare cause of respiratory failure and descending weakness in the United States, caused by prevention of presynaptic acetylcholine release at the neuromuscular junction. This presentation has several mimics, including myasthenia gravis and the Miller-Fisher variant of Guillain-Barré. It may be caused by ingestion of spores (infant), ingestion of pre-formed toxin (food-borne), formation of toxin in vivo (wound-associated cases), through weaponized sources, or through inappropriately administered injections (iatrogenic). Cases of black tar heroin injection have been associated

SUBMITTER: Hoffman T 

PROVIDER: S-EPMC10332679 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature