Symbiont-host interactome mapping reveals effector-targeted modulation of hormone networks and activation of growth promotion.

ABSTRACT: Plants have benefited from interactions with symbionts for coping with challenging environments since the colonisation of land. The mechanisms of symbiont-mediated beneficial effects and similarities and differences to pathogen strategies are mostly unknown. Here, we use 106 (effector-) proteins, secreted by the symbiont Serendipita indica (Si) to modulate host physiology, to map interactions with Arabidopsis thaliana host proteins. Using integrative network analysis, we show significant convergence on target-proteins shared with pathogens and exclusive targeting of Arabidopsis proteins in the phytohormone signalling network. Functional in planta screening and phenotyping of Si effectors and interacting proteins reveals previously unknown hormone functions of Arabidopsis proteins and direc

SUBMITTER: Osborne R 

PROVIDER: S-EPMC10333260 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature